In digital age there are photoshop filters to imitate film grain. It's not important. Anyway, no filter can reproduce an impression of shining crystals of silver in a layer of emulsion.
I have my own theory of artistic media. Any artistic media has a special characteristic which I name as "degree of resistance". Natural stone has the most high degree of resistance. What can you depict if you have a stone wall of cave and another stone in your hand only? Next step: you have an ochre, soot and stone wall in cave. Well, you understand me. Let's remember about Leonardo, who spend a lot of time to investigate new paints and so on. Now. We have digital media and some tools (software) to create something. It's evident, digital canvas is a media which has "zero degree of resistance", because we can do everything with any pixel of our canvas. Oil, aquarelle, acryle, charcoal, ink? Fuck! We don't need this shit anymore
What are consequences of this freedom? OMG! All modern digital artists trying to look more artistic and trying to add ARTIFICIAL effects of stroke, "natural" dirt etc...
So I think: some "degree of resistance" is very important. And we just can not use this freedom of media, which modern technology gives us. Engineers in our time are better than artists.